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Morozov V.G., Khavinson V.K

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Bor MV, Von castel-roberts KM, Kauwell GP, et al

The procedure takes approximately 1 to 2 hours

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However, although these activated progenitors produce mature OLGs in the cuprizone model, the process fails in EAE, suggesting that inflammation (in EAE) may lead to an overactivation of GPR17, thereby preventing the terminal differentiation of OPCs (Coppolino et al., 2018)