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Neural Plast 2012:704103
Basic FGF or VEGF Gene Therapy Corrects Insufficiency in the Intrinsic Healing Capacity of Tendons

The higher 30mg dose over 12 weeks produced 8.1 kilograms of loss, with nearly 96 percent of participants hitting the clinically meaningful threshold of 5 percent body weight reduction

Comprehensive toxicology evaluations reveal that the compound does not affect food intake, body temperature regulation, or basic physiological parameters at effective doses in animal models, indicating that its metabolic effects occur through specific pathway modulation rather than general physiological disruption
