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[141] in 2007 examined the association of multiple polymorphisms: MTHFR C677T and A1298C, MTR A2756G, MTRR A66G, BHMT G742A, and CBS 68-bp ins

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CVOs enable a diet induced CNS glutamate (excitatory)/GABA (inhibitory) imbalance to precipitate not only POTS but also symptoms that involve decreased oxytocin, vasopressin (ADH), Corticotropin Releasing Hormone (CRH for ACTH), and Gonadotropin Releasing Hormone (GnRH for LH, FSH) [50,51]