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doi: 10.1080/27697061.2023.2291789 572 ValderSStaltnerRBizjakDAEsatbeyogluTHerdegenVKpselMet al

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A separate study focused on the NOTO and NOTO -related genes roles in the commitment of mesendoderm progenitor cells towards a notochordal fate by maintaining an expression of the regulatory factors FoxA2 and T-brachyury ( NOTO -eGFP reporter in a human pluripotent stem cell (hPSC) line using CRISPR/Cas9-mediated genome editing that was verified by comparing them to two human NP cell transcriptome datasets (Zhang et al., 2020)