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TGF- pathway Ionizing radiation-induced ROS activate latent TGF-1 by oxidizing Met253 in its LAP, triggering conformational changes, suggesting the isoform specificity of ROS in TGF- activation

The aforementioned findings indicate that neurons might influence astrocyte protein expression by emitting miRNA-containing exosomes, which could be involved in the pathogenesis of neurodegenerative conditions
[DOI] [PubMed] [Google Scholar] 368.Estevez AG, Sampson JB, Zhuang YX, Spear N, Richardson GJ, Crow JP, Tarpey MM, Barbeito L, Beckman JS

Biochemistry 36 , 49254933 (1997)
