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Itaconate and related derivatives can activate Nrf2 and limit ROSMAPKNF-B signaling and pyroptosis, which reduces myeloid infiltration and downstream cytotoxic T-cell skewing [33]

p Values were adjusted for multiple comparisons using Holms step-down Bonferroni correction

#87110901) were cultured in S-MEM (Gibco) supplemented with 1x GlutaMAX (Gibco), 1x Penicillin-Streptomycin (Gibco) and 10% FBS (Gibco) at 37 C and 5% CO 2 between 0.2 and 0.7 10 6 cells/mL

Autophagy 10 , 14031414 (2014)

& Mohammadi-Samani, S

5.4.2 PCs and diabetic retinopathy Diabetic retinopathy (DR) is a significant microvascular complication of diabetes mellitus and a leading cause of vision loss worldwide (Tan and Wong, 2022