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Description
When glutamate was injected into the ganglia innervating the temporalis or masseter muscle, there was a significant increase in nociception (decrease in afferent mechanical thresholds) that was attenuated by NMDAR antagonists (2R)-amino-5-phosphonovaleric acid, AP-V) or worsened by EAAT blockers (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid, TFB- TBOA) [267]
Adult-onset renal thrombotic microangiopathy and pulmonary arterial hypertension in cobalamin C deficiency
StudyTeam aggregates enrollment data from multiple investigative sites screen rates, enrollment rates, dropout rates, and protocol deviation frequencies into a centralized analytics dashboard that allows enrollment operations teams to identify underperforming sites, reallocate resources, and implement targeted interventions based on data signals rather than lagging summary reports
Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6
J Cereb Blood Flow Metab 21: 929936
showed IGF-1 overexpression increased muscle mass 15-30% and improved strength in aged mice
