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Research also shows that inositol is a simple and safe treatment that is capable of improving reproductive axis functioning in PCOS patients, reducing the hyperinsulinemic state that affects LH secretion and restoring spontaneous ovarian activity and consequently clinical pregnancy rate

Dietary or supplemental L-carnitine that is not absorbed by enterocytes is degraded by colonic bacteria to form two principal products, trimethylamine and -butyrobetaine

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The third one is that the follow-up duration for these studies ranged from seven days to three years, which may result in potential publication bias and reduce the reliability of these trials