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BPC-157, by contrast, modulates growth factor pathways (VEGF, FGF, NO system) involved in tissue repair without directly activating hormone receptors (Sikiric et al., J Physiol Pharmacol 2018)

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However, as described before, this reaction does not seem to be physiologically relevant (Kang et al., 2021)

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CREB regulates gene expression of dynorphin, a protein that slows dopamine release, dampening the reward system

This visual property is a normal aspect of its formulation