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In addition, we summarize the drivers of accelerated immunosenescence in PWH, including amplification of the senescence-associated secretory phenotype (SASP) arising from persistent low-grade inflammation and immune activation, as well as mitochondrial dysfunction jointly induced by HIV proteins (e.g., Vpr) and specific antiretroviral regimens (Fig

Shungu, D

Handbook of Cancer and Immunology

10.1093/ajcn/73.2.444s 68 IyerN.VaishnavaS
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Molecules 29:1729 [DOI] [PMC free article] [PubMed] [Google Scholar] Tadagavadi RK, Reeves WB (2010) Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells
