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7 Meanwhile, the C max of panduratin A after oral administration of 45 mg/kg of panduratin A-consisted fingerroot extract surpassed the IC 50 value by approximately 10-fold of that obtained in an in vitro study using SARS-CoV-2, and the minimum plasma concentration at 24 h remained approximately 4-fold higher than the IC 50 value
Apparently, the ameliorative effects against oxidative stress or undesired pro-inflammatory response remain the predominant mechanisms by Moringa oleifera extracts protect against complications of T1D in preclinical (animal) models
Ethics statement The animal study was approved by Ningxia Medical University Ethics Committee
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