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P.WangJ
This underscores that mimicking a more physiological environment enables a more accurate representation of pathogenic potential in in vitro infection models
Lack of SMARCA4 inhibits expression of the aldehyde dehydrogenase ALDH16A1 that binds to the Trx1 active site and inhibits its function but also promotes lysosomal degradation of the redoxin [95]
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On the other hand, smoking cessation can lead to a gradual normalization of these metabolic pathways, similarly affecting the pharmacokinetics of drugs
