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During intense physical activity or stress, glutamine levels can drop significantlysometimes by up to 50% after prolonged exercisemaking supplementation valuable for certain individuals

These mechanisms contribute to the pressor effect of caffeine contained in EDs and contribute to producing positive chrono- (increase in heart rate) and inotropic (increase in myocardial contractility) effects and an increase in blood pressure

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The first step is to consult your healthcare provider so they can guide you to the best treatment option for your situation

10.1186/s12885-015-1965-7 123 LinD.KuangG.WanJ.ZhangX.LiH.GongX.et al (2017)

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