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This effect of AMPK signaling is in agreement with our previous studies showing that, despite having 15% and 40% of WT total and mitochondrial GSH levels (respectively), livers from nave GCLM KO mice maintain structural and functional integrity of the mitochondria and show induction of ER stress-related genes 17,38

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Although epidemiological data favorably show a negative relationship between drinking tea and the preponderance of AD in that part of the country, any correlation between tea consumption and AD prevalence should be evaluated with caution because the effects of racial differences, dietary preferences, and lifestyle cannot be excluded (92)

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[DOI] [PubMed] [Google Scholar] 35.Kinnula VL, Fattman CL, Tan RJ, Oury TD