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Reporting followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) where applicable, with emphasis on transparent identification of available evidence rather than quantitative pooling

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A number of studies report frequent collections of B cells (diffuse distribution, more focal aggregates or even follicle-like structures) in up to 40% of MS patients at various stages of disease (Jain and Yong, 2021)

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