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Building on this, they developed a biocompatible material designed for sustained glutamate release, which promoted neuroprotection and axon regeneration in vivo following ONI [18]

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NNMT had previously been identified as upregulated in obese adipose tissue, several solid tumours, and ageing tissue more broadly, where its activity correlates with depleted SAM and elevated 1-methylnicotinamide (MNA)

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