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Description
5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."
Important Notes Practical points that keep administration safe and consistent
10.1152/ajpendo.00050.2011 154 WilliamsA
In the Neelakantan study, diet-induced obese (DIO) C57BL/6 mice were treated with NNMT inhibitors including 5-Amino-1MQ analogues
K.KalaniA.GivvimaniS.SathnurP
doi: 10.1080/14728214.2017.1269744
