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We employed typical acute pancreatitis models in vivo and in vitro and found that VB 12 activated CBS-SIRT1 axis to suppress oxidative stress and repair mitochondrial damage in the pathological process of acute pancreatitis

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This provides adequate systemic exposure while remaining within commonly researched dose ranges

Lancet 377:19291937 Creager MA, Olin JW, Belch JJ, Moneta GL, Henry TD, Rajagopalan S, Annex BH, Hiatt WR (2011) Effect of hypoxia-inducible factor-1alpha gene therapy on walking performance in patients with intermittent claudication

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Take shilajit on an empty stomach in the morning for optimal absorption