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You just excrete the extra through urine, she explained

CBD pretreatment increased cell viability and the gene expression of the pro-survival chaperone GRP78 and the neurotrophic factor MANF, while decreasing the expression of pro-apoptotic markers such as BIM and caspase-12, indicating that CBD may protect against endoplasmic reticulum stress-induced cell death [87]

Like hot stress, cold stress induces an excessive generation of ROS, leading to attenuation of the plants ROS scavenging ability, disrupting ROS homeostasis

10.1038/s42255-020-00319-x [DOI] [PMC free article] [PubMed] [Google Scholar] Mason, J

However, the mechanisms underlying this relationship remain unclear, and further studies are needed

Scavenger receptors, oxidized LDL, and atherosclerosis