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Strategies and challenges of CAF-targeted therapy Although some therapeutic strategies have shown promising results in preclinical studies, particularly in enhancing anti-cancer immune responses mediated by IFN- and TNF-, and promoting CD8 + T cell cytotoxicity, CAF-targeted therapies still face several challenges, especially in improving the specificity of treatment and reducing systemic side effects

10.1038/s41573-021-00233-1 68 FountoulakisP.KourampiI.TheofilisP.MarathonitisA.PapamikroulisG
[DOI] [PubMed] [Google Scholar] 51.Szabo S

Plasma or serum in therapeutic drug monitoring and clinical toxicology

M., & Steinbuchel, A

Consistency matters more than intensity, since steady glutathione levels are what sustain the brightening effect over time
