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This high binding capacity allows FR to transport folate against a concentration gradient at levels as low as 0.1 nM [5, 26], roughly ten times lower than required transport via RFC [2, 3], making it the most efficient plasma membrane folate transporter identified

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The American Society of Clinical Investigation / The Association of American Physicians (ASCI/AAP) Joint Meeting

Glucose metabolism in astrocytes provides the necessary metabolic substrate to respond to the energy needs of neurons, ensuring their normal functions

In mouse myocardial infarction models, TB-500 reduced infarct size, decreased fibrosis, and improved left ventricular ejection fraction

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