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Lentinus edodes contains lentinan, terpenoids, and steroids that exert anticancer effects against lung carcinoma and colon cancers by inducing the expression levels of p21, BAX, and caspase 3 and 9 and suppressing that of Bcl2, resulting in cancer cell death and cell cycle arrest in the G 0 /G 1 phase [133]

Nicotinamide riboside (NR) is a precursor that the body converts into NAD+, while NAD+ is the final form used in cellular processes

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The reduced form of glutathione is a highly active form to neutralize free radicals and reduce oxidative stress in the body

After Kla treatment, ALDOA activity was reduced, and its catalytic function was suppressed, establishing a negative feedback loop
Glutathione may indirectly contribute to a brighter, more luminous complexion by lowering toxic levels and supporting cellular health
