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One characteristic of renal cell death and a potential contributor to gentamicin-induced ARF is caspase-3, an essential component of programmed cell death (apoptosis) 88

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Sandilands EA, Bateman DN

The IGF Signaling Axis The insulin-like growth factors (IGFs) belong to the insulin and IGF signaling (IIS) pathway, which is comprised of a network of ligands, receptors, and binding proteins that mediate signaling to control and coordinate normal organismal growth and metabolism (Figure 1)

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