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doi:10.1073/pnas.0701096104 Zhang C, Rodriguez C, Spaulding J et al (2012) Age-dependent and tissue-related glutathione redox status in a mouse model of Alzheimers disease

Future investigations into the possibility of regenerative and customized therapy, as well as the intricate interactions between oxidative stress and other pathogenic pathways in hearing loss, should be the main priorities

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Animals were anesthetized and maintained using isoflurane (1-2% in O 2 ) and placed head first in the prone position

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Oxidative damage to lens proteins, particularly crystallins, leads to protein denaturation, aggregation, and cross-linking, reducing transparency