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DNA repair can occur due to overexpression of repair proteins such as PARP1, wee-like protein kinase 1 (WEE1), Chk1, Rad3-related protein (ATR) and ataxia telangiectasia mutated (ATM) protein kinase ( SCLC resistance to the platinum series of drugs occurs, in part, due to the repair of DNA damage ( via glutathione (GSH)

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