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Differential gene expression was calculated for RNA-Seq data sets using DESeq2 (103)

doi:10.2174/157015909787602788 Kappos L, Gold R, Miller DH, Macmanus DG, Havrdova E, Limmroth V, Polman CH, Schmierer K, Yousry TA, Yang M, Eraksoy M, Meluzinova E, Rektor I, Dawson KT, Sandrock AW, ONeil GN, BG-12 Phase IIb Study Investigators (2008) Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

MT can facilitate tumor cell growth or drug resistance by two potential mechanisms (Figure 1)
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