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Originally identified in the early 1990s, BPC-157, short for Body Protection Compound 157, also known as Gastric Pentadecapeptide, is a synthetic peptide composed of 15 amino acids and derived from a protective protein sequence found in human gastric juice

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Redox signaling: Hydrogen peroxide as intracellular messenger

Three prominent examples include, (i) phosphorylation and recruitment of voltage-gated Ca2+ channels in heart to increase contractility, (ii) phosphorylation of phosphorylase kinase, which in turn phosphorylates phosphorylase, which releases glucose-1-phosphate from glycogen and boosts energy metabolism in liver, and (iii) response to odorants by sensory neurons in the olfactory epithelium by direct action of cAMP on opening of cAMP-gated ion channels of the plasma membrane of olfactory neurons

Identification of hybrid insulin peptides (HIPs) in mouse and human islets by mass spectrometry