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In the present study, elevated PGA levels were observed among 89% of symptomatic TTR-V30M patients and in 63% of asymptomatic carriers relative to the median of healthy controls (Table 1)

During the inflammatory process, macrophage metabolism undergoes a shift from oxidative phosphorylation to glycolysis, with HIF-1 emerging as a central regulator

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Signaling pathway involving release and caspase 3 activation is conserved

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