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For example, cis-3-(9H-purin-6-ylthio)acrylic acid (PTA) is a prodrug of the antitumor and immunosuppressive antimetabolite 6-mercaptopurine that requires GSH conjugation and subsequent metabolism for activation (Gunnarsdottir and Elfarra, 1999)

[DOI] [PMC free article] [PubMed] [Google Scholar] 355.Vartsky D, et al

The remaining 304 articles were removed for the following reasons: they did not focus on the 677C allele of the MTHFR gene

Stres, prmyslov zpracovan potraviny, nedostatek pohybu i spnku a k tomu ivot v prosted plnm kodlivin dlouhodob psoben tchto faktor me postupn vst ke vzniku chorob souvisejch se strnutm

Regarding the kidney tissues, the epithelial cells of renal tubules showed vacuolar degeneration, damaged brush borders, and the presence of protein casts in the LPS group, unlike in the control group (Figure 3B)