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The development of psoriasis is associated with genetic predisposition which has a basis of T cell activation secondary to dermal inflammation with abnormal keratinocyte proliferation
Its multifaceted approach, including appetite suppression and slowed gastric emptying, has been shown to result in significant reductions in body fat

doi: 10.1016/j.devcel.2025.02.004 27 JiangLKonNLiTWangSJSuTHibshooshHet al
10.1371/journal.pone.0134235 PLoS One 109 SthijnsM
Furthermore, HPP971 has completed two phase-I studies for the treatment of several diseases, including blood, bone, eye, kidney, and lung diseases, where it was well tolerated [66]
