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By the eighth day, ISCs co-cultured with CM from old intestinal organoids exhibited a significant decrease in intestinal organoids and organoid buds compared to those co-cultured with CM from young intestinal organoids (Fig

As a dietary supplement, L-carnitine offers advantages including favorable safety profile, convenient administration, and potential efficacy, positioning it as a promising adjunctive option for MASLD management

Composition: calcium carbonate, magnesium oxideAnalytical ingredients: protein 24.3%, crude fat 0.1%, crude fibre 0.2%, crude ash 41.4%, hydrochloric acid insoluble ash 38.4%Nutritional additive per kg: L-carnitine 450 g Feeding recommendation: dog: vegetarian food plan: per 10 kg body weight: 1 x 0.7 g for heart and liver: per 10 kg body weight 3 x 1 g cat: 1 x 0.7 g

Finally, we observed no effects of ALCAR in inducing cell cycle arrest, both in the PCa and BPH cell lines (Additional file 1: Figure S2 a-d)

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