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Niacinamide is safe for use in pregnant and breastfeeding patients and is generally applied alone as 45% cream twice daily or in association with other lighteners, such as kojic acid and arbutin
Based on whether these cells stay alive without replicating, replicate, or die in the next time steps, the population can eventually either expand and grow exponentially or go extinct
The primary antibodies used in the study included anti-AKT (1:1,000, Affinity Biosciences, Changzhou, China), anti-p-AKT (1:1,000, Cell Signaling Technology, Shanghai, China), anti-p38 MAP kinase (1:1,000, Affinity Biosciences), anti-phosphorylated p38 (1:1,000, Cell Signaling Technology), and anti--actin (1:2,000, Sangon, Shanghai, China)
10.1111/ejn.16035
doi: 10.1074/jbc.M114.621383
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