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Although these strategies enhance the delivery of drugs to the brain through ligand-receptor interactions, they have limitations, such as dependence on high receptor expression and the potential for immune responses or receptor downregulation

Senolytics: targeting senescent cells for age-associated diseases

The accumulation has the potential to influence the blocking and clearance functions of the brain barrier, and can interfere with the synthesis, release, and reuptake of neurotransmitters, resulting in abnormal neurological functions (Xi et al., 2025

Inflammation Modulation Investigated for its potential to reduce inflammation in various tissue injury models

While large-scale clinical trials in human subjects remain an area of ongoing investigation, the preclinical data consistently demonstrates positive effects on follicular cell activity

The promotion and prescription of BPC-157 without FDA approval undermines these regulatory processes