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Current findings suggest that active components in herbal medicine (e.g., curcumin, resveratrol) activate the Nrf2 pathway by covalently modifying cysteine residues on Keap1 protein (Nosrati-Oskouie et al., 2022)

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For those looking to avoid gastrointestinal side effects while still reaping the performance benefits of nitric oxide production, L-citrulline offers a safer and more effective solution
