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Metformin recipients also had significantly higher levels of homocysteine and methylmalonic acid (markers of B12 deficiency) and significantly worse scores on standardised clinical assessments of the severity of neuropathy

(PubMed) Grothe J, Riethmuller J, Tschurtz SM, et al

Safety data indicate mostly mild gastrointestinal events (nausea, diarrhea, vomiting), dose-dependent, and often improved with titration

in the real world, the risk stems from how its sold, dosed, and used

Instead of chasing quick fixes, they focus on nourishing the specific cellular pathways that keep tissues functioning optimally

A novel ferroptosis related gene signature is associated with prognosis in patients with ovarian serous cystadenocarcinoma