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The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)

Jan 23 2021;397(10271):319-333

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[2] Sikiric et al

Mutations in the gene encoding filamin B disrupt vertebral segmentation, joint formation and skeletogenesis

obese-animal weight gain attenuated
