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Key Takeaway: Glutathione is the body's primary defense against oxidative stress, but its effectiveness as a supplement depends entirely on how well your body can absorb it through the digestive tract

In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

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