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Regulating TAM iron metabolism within the TIME, specifically by promoting iron uptake and storage in M2-type macrophages while inhibiting iron release, allows iron accumulation in TAMs to enhance ROS production, increase p300/CBP acetyltransferase activity, and promote p53 acetylation

2010;298:G364G374

Brschweiler S, Fuchs JE, Bader G, Schrank E, Stefan E, Huber RG (2021) A step toward NRF2-DNA interaction inhibitors by fragment-based NMR methods

Biofactors 2009

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