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m 6 A-methylated RNA is recognized by readers, such as YT521-B homology (YTH) domain family proteins (YTHDF1, YTHDF2, YTHDF3, and YTHDC1) and heterogeneous nuclear ribonucleoprotein family proteins (HNRNPA2B1 and HNRNPC), which determine the fate of the marked RNA, such as degradation, translation or splicing[144-147] (Figure 4A)

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