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PMI: a DeltaPsim independent pharmacological regulator of mitophagy

The human CHAC2 protein predates CHAC1, with the two sharing only 50% sequence identity (Nguyen et al., 2020)

doi: 10.3389/fmicb.2019.02324 269 RaphaelINalawadeSEagarTNForsthuberTG

Mitochondria also host antioxidant enzymes such as superoxide dismutase (SOD) and catalase as the first line of defense against ROS by converting superoxide to H 2 O 2 and subsequently to water

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Transmembrane electron transfer by the membrane protein DsbD occurs via a disulfide bond cascade
