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Moreover, the gut microbiota system and its metabolites can change the immuno-inflammatory state (93), which is indicated by the abnormal production of chemokines, cytokines and inflammatory markers (94)

N.LottJ

Their biocompatibility is critical to ensure they do not elicit a negative immune response

Effects of Sulforaphane in In Vitro MS Models Since demyelination determines the activation of inflammatory cells, such as macrophages and microglia, that release cytotoxic mediators like ROS and TNF-, with a consequent loss of oligodendrocytes and axonal damage, strategies useful to counteracting the neuroinflammation and neurodegeneration are necessary [118,119]

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