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Melatonin interaction through membrane receptors with G proteins leads to a decrease in intracellular cAMP with a simultaneous increase in calcium ion concentration and activation of phospholipase C

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ARF was created by daily gentamicin (GN) administration for seven consecutive days and various treatment protocols, including chitosan (CS) NPs, spanlastics NPs, as well as conventional, NP formulations of GSH, LS, and their respective combinations