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doi:10.12688/f1000research.1113.3

ERK1/2 Inhibition Overcomes Resistance to BCL2 Inhibition in acute myeloid leukemia by impact on mitochondrial dynamics and function

2013;3(2) [Google Scholar] 85.Uruno A., Yagishita Y., Yamamoto M

Okcu MF, Wang RY, Bueso-Ramos C, Schober W, Weidner D, Andrassy R, Blakely M, Russell H, Ozkan A, Kuttesch J, Andreeff M , Chan KW, Ater J

For example, the LEADER trial showed that Liraglutide significantly reduced the risk of major adverse cardiovascular events (MACE) by 13% and cardiovascular death by 22% in comparison to placebo

The consequent ROS accumulation in the body is inevitably associated with tissue injury [1], since ROS are known to damage cell components, particularly DNA, leading to loss of function, induction of apoptosis, or even carcinogenesis [2]