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Wat ze vonden: In de controlegroep stierf 70 % van de ratten binnen 30 dagen In de BPC-157-groep stierf slechts 10 % Histologie: snellere vorming van collateralen, normalisering van de druk in de poortader, 80 % reductie van trombosen in de lever Waarom dit belangrijk is: Dit zijn extreme omstandigheden

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The binding of C-Met to HGF initiates the receptors innate kinase activity, followed by the formation of a multisubstrate docking site for the intracellular junction protein, which recruits signaling molecules due to homologous dimerization and autophosphorylation at Tyr1234 and Tyr1235 and subsequent phosphorylation at Tyr1349 and Tyr1356 at the c-terminal tail (Birchmeier et al., 2003

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