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The mechanistic rationale for combining the two is straightforward

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Circadian rhythms influence renal electrolyte excretion, which affects blood osmolarity and indirectly influences ocular hydration and IOP regulation (Mills, 1966
Alzheimers disease AD is a neurodegenerative condition with gradual onset and progressive impairment of behavioral and cognitive functions

The cantilever is then retracted from the substrate

PMID: 31 YangHLiQChenXWengMHuangYChenQet al
