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This includes the design of more potent and selective SIRT1 modulators and the evaluation of their efficacy in preclinical models of diseases characterized by ferroptosis, such as kidney diseases, neurodegenerative disorders, and cancer

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Journal of Ethnopharmacology 26811356910.1016/j.jep.2020.113569 141 ZhaoX.XueX.WangC.WangJ.PengC.LiY

In NAFLD, FMT is a novel strategy to modify gut microbiome and achieve metabolic balance [103]

In addition, TXN acts as an antioxidant by facilitating the reduction of oxidised proteins through cysteine-thiol-disulfide bond exchange [81, 82]