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Compared with CcSOD1, TAT-CcSOD1 protein could be rapidly and efficiently transported into HaCaT cells

US20210186943A1 - Otic formulations for drug-induced ototoxicity - Google Patents Otic formulations for drug-induced ototoxicity Download PDF Info Publication number US20210186943A1 US20210186943A1 US17/050,421 US201917050421A US2021186943A1 US 20210186943 A1 US20210186943 A1 US 20210186943A1 US 201917050421 A US201917050421 A US 201917050421A US 2021186943 A1 US2021186943 A1 US 2021186943A1 Authority US United States Prior art keywords formulation otic composition therapeutic agent agent Prior art date Legal status (The legal status is an assumption and is not a legal conclusion

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Laboratory investigations have examined its interactions with growth factor signaling, nitric oxide pathways, and fibroblast activity in tissue culture and preclinical contexts

A relationship between long-term metformin use and vitamin B12 deficiency has been long discussed, and many readers will have come across this in clinical practice

Other Drugs That Affect Vitamin B12: Metformin users may also take other medicines that can decrease vitamin B12 levels
