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FIGURE 4 3.5 FOXO4-DRI inhibits FOXO4-P53 binding and promotes P53 phosphorylation To further elucidate the specific mechanism of FOXO4-DRI in anti-aging, we induced senescence in endothelial cells under OGD conditions and treated these cells either PBS or FOXO4-DRI

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature Medicine , 20(4), 398-403

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SUNBEAM compared ozanimod with interferon beta-1a in patients with relapsing multiple sclerosis over 12 months
