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doi:10.1155/2013/942030
Figure 6 Nuclear GSTP Inhibits HMGB1 Phosphorylation and Increases its DNA-Binding Affinity Classic protein kinase C has been reported to enter the nucleus and act as an upstream kinase of HMGB1 in LPS-stimulated macrophages and promotes HMGB1 to export from the nucleus to cytoplasm (30)
[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Panickar K.S., Jewell D.E
Plos Genet 16:e1008640
R.ShanZ
Using a multifaceted approach, we demonstrate that reducing GSH biosynthesis led to acute degradation of RUNX2, impaired osteoblast differentiation, and reduced bone formation
