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10.47799/pimr.1003.13 63 KamatP

Italian Journal of Pediatrics

As noted, the present knowledge is limited, and these are considerations, not strong recommendations

A meta-analysis of 12 clinical trials measuring flow-mediated vasodilation (FMD
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Metformin, a widely used AMPK activator, has oral bioavailability of approximately 5060%, but it compensates with high doses (1,0002,000 mg daily)
